Plasmodium falciparum

*Plasmodium falciparum* field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype

Multiple transcontinental waves of drug resistance in *Plasmodium falciparum* have originated in Southeast Asia before spreading westward, first into the rest of Asia and then to sub-Saharan Africa. In vitro studies have suggested that hypermutator …

Independent emergence of artemisinin resistance mutations among *Plasmodium falciparum* in Southeast Asia

BACKGROUND: The emergence of artemisinin-resistant *Plasmodium falciparum* in Southeast Asia threatens malaria treatment efficacy. Mutations in a kelch protein encoded on *P. falciparum* chromosome 13 (K13) have been associated with resistance in …